文献汇报——辉.pptVIP

Development of an online SPE–LC–MS-based assayusing endogenous substrate for investigation of solubleepoxide hydrolase inhibitors 报告人：谢辉 2011年6月29日 Background 1.Therapeutic potency of sEHI sEH inhibitors are a promising new class of potential drugs for treatment of a variety of diseases, for example inflammation, hypertension, and pain. 2. New assays are needed Analytical techniques are needed to identify active compounds and quantitatively measure their potencies. 3. Development of new assay electrospray ionization tandem mass spectrometry (ESI–MS–MS) (电喷雾离子阱质谱) Merits