3章 第3节 原核和真核染色体结构.pptVIP

串联基因簇Tandem (串连) gene clusters: rDNA: 45S precursor (18,5.8 28S) – 10-10000 copies (human: ca. 5x40); histone genes: 100. 中度重复序列 (10-100/1000 level) 分散重复DNA(Dispersed (分散) repetitive DNA): e.g. Alu and L1 elements. 单一序列DNA Dispersed repetitive DNA: Human Alu elements: 300bp, 300000 –500 000 copies of 80-90% identity L1 element: Alu and L1: almost 10% of human genome. Transposition (转座), as selfish or parasitic DNA, role in evolution Highly repetitive (高度重复): Satellite DNA (卫星DNA) Mouse genome DNA Satellite DNA: 30% GC EcoR I: 234bp band Repeats: GAAAAA(A/T)(G/C)T 5’ – ATAAACTATAAACTATAAACT –