神经系统退行性疾病基础-培训课件.pptVIP

What Is Alzheimer Disease ? Alzheimer Disease Growth in U.S. Population Aged 65+, 75+, and 85+ Genes Associated with Alzheimer Disease Classification of Senile Dementia DSM-IV分类 1.阿尔茨海默病 (AD) 2.血管性痴呆 (CVD) 3.脑外伤所致痴呆 4.Parkinson病所致痴呆 5.Huntington病所致痴呆 6.HIV病所致痴呆 7.Pick病所致痴呆 8.Creutzfeldt-Jacob病所致痴呆 9.物质和躯体病所致痴呆 10.其它痴呆(Lewy body dementia) AD clinical symptom 认知性症状 Sulfo-glycosaminoglycan content affects PHF-tau solubility and allows the identification of different types of PHFs PS1 may act as a molecular tether, connecting GSK-3? with important substrates. Effects of GSK-3b on AD Hi