复方中药丹星通络汤对大鼠局灶性脑缺血再灌注损伤的保护作用论文.docVIP

　　复方中药丹星通络汤对大鼠局灶性脑缺血再灌注损伤的保护作用论文 【关键词】 复方丹星通络汤；脑缺血;再灌注损伤;乳酸脱氢酶；FAS 【Abstract】 AIM: To study the neuroprotection and mechanism of danxingtongluotang （DX） on rats iareperfusion (I/R) injury. METHODS: Forty SD male rats ly into 4 groups: control group, shamoperated + normal saline (NS); model group, cerebral I/R+NS; nimodipine group, I/R+nimodipine; DX group, I/R+DX. The 4 groups odipine or DX for consecutive 5 d. Focal I/R models ade ethod. After cerebral ischemia for 2 h and then reperfusion for 24 h, the activity of LDH in serum easured and the expression of FAS in brain tissue of model grou