有机化学chap02stereochemistry2.pptVIP

* * * * 1951年J.M.Bijvoet通过X射线分析法，测得了右旋酒石酸铷钠盐的构型，这种实际测定得构型称为绝对构型。因此推出人为规定的甘油醛的构型与实际的构型完全符合。 * * * * * * * * * * * * * * * * 巴斯德(Pasture)发现结晶洒石酸，左旋体半面结晶向左，右旋体半面结晶向右。在放大镜下，他用镊子分开两种酒石酸。 * ?Louis Pasteur?was the first to conduct chiral resolution when he discovered the concept of?optical activity?by the manual separation of left-handed and right-handed?tartaric acid?crystals in 1849. In 1882 he went on to demonstrate that by?seeding?a?supersaturated?solution of?sodium ammonium tartrate?with a d-crystal on one side of the reactor and a l-crystal on the opposite side, crystals of opposite handedness