2005-2006年北京地区肠道致病菌的分布及耐药状况.pdfVIP

中国抗生素杂志2007年 12月第32卷第 12期 ·745· 文章编号：l001—8689(2007)l2-0745—03 2005~2006年北京地区肠道致病菌的分布及耐药状况 刘立明 曲芬。 崔恩博 郭桐生 李筱涵 廖华芳 (中国人民解放军第302医院临检中心， 北京100039) 摘要： 目的 监测近两年北京地区肠道致病菌的组成、流行趋势及耐药状况，为本地区的流行病学研究及临床合理用药提供 依据。方法 通过常规大便培养，筛选出致病菌后经生化及血清学进一步鉴定到种、群或血清型。结果 肠道致病菌感染以男性为 主，成年人多发，7～10月为腹泻发病高峰。病原以志贺菌属居首位，其次是弧菌；在志贺菌属中，宋内菌构成有增加趋势。各菌属及 志贺菌属内各种群对抗生素的敏感率有差异。结论 北京地区感染性腹泻的病原种类繁多，有性别、年龄、季节的分布特点，耐药性 不同，应重视监测。 关键词；肠道致病菌；分布； 流行； 耐药性；腹泻 中图分类号：R375 文献标识码：A Distribution and resistance of enteric pathogenic bacteria in Beijing area from 2005 to 2006 I iu I．i—ruing， Qu Fen， Cui En—bo。 GuoTong—sheng， Li Xiao—han and Liao Hua-fang (The Center of Clinical Laboratory ofthe 302th Hospital，PLA， Beijing 100039) ABSTRACT Objective To monitor the distribution，epidemic and resistance of enteric pathogenic bacte— ria in Beijing area in the last two years and to offer the data for guiding epidemiologic study and clinical treat— ment． Methods Enteric pathogenic bacteria were cultured and identified to species，group and serotype with the biochemical and serological test．Then the susceptibility of bacterium to antimicrobial agents was tested． Results Enteric pathogenic bacteria infections mostly in occurred male，adult patients，and became epidemic in July，August，September and October．Shigella spp．and Vibrio spp．were the main paxhogenic bacteria of intestinal tract while，the rates of Shigella sonnei rose in Shigellae spp．，and with different antibiotic suscepti— bilites among them． Conclusion There were many species of enteric pathogenic bacteria causing infective diarrhea in our hospita1．Their distributions were different in sexes．ages and seasons．The resistance rate was different，and surveillance should b