- 1、本文档共10页,可阅读全部内容。
- 2、原创力文档(book118)网站文档一经付费(服务费),不意味着购买了该文档的版权,仅供个人/单位学习、研究之用,不得用于商业用途,未经授权,严禁复制、发行、汇编、翻译或者网络传播等,侵权必究。
- 3、本站所有内容均由合作方或网友上传,本站不对文档的完整性、权威性及其观点立场正确性做任何保证或承诺!文档内容仅供研究参考,付费前请自行鉴别。如您付费,意味着您自己接受本站规则且自行承担风险,本站不退款、不进行额外附加服务;查看《如何避免下载的几个坑》。如果您已付费下载过本站文档,您可以点击 这里二次下载。
- 4、如文档侵犯商业秘密、侵犯著作权、侵犯人身权等,请点击“版权申诉”(推荐),也可以打举报电话:400-050-0827(电话支持时间:9:00-18:30)。
- 5、该文档为VIP文档,如果想要下载,成为VIP会员后,下载免费。
- 6、成为VIP后,下载本文档将扣除1次下载权益。下载后,不支持退款、换文档。如有疑问请联系我们。
- 7、成为VIP后,您将拥有八大权益,权益包括:VIP文档下载权益、阅读免打扰、文档格式转换、高级专利检索、专属身份标志、高级客服、多端互通、版权登记。
- 8、VIP文档为合作方或网友上传,每下载1次, 网站将根据用户上传文档的质量评分、类型等,对文档贡献者给予高额补贴、流量扶持。如果你也想贡献VIP文档。上传文档
查看更多
USP61-微生物限度微生物计数.pdf
58 〈55〉 Biological Indicators—Resistance Performance Tests / Microbiological Tests USP 36
It is preferable to use the same method as that defined by ENUMERATION METHODS
the biological indicator manufacturer to determine D values.
The use of a different method can result in differences that Use the Membrane Filtration method or one of the Plate-
are more an artifact of the method than a variation in the Count Methods, as directed. The Most-Probable-Number
performance of the biological indicator. (MPN) Method is generally the least accurate method for
microbial counts; however, for certain product groups with
Survival Time and Kill Time very low bioburden, it may be the most appropriate
method.
Take two groups, each consisting of 10 specimens of the The choice of a method is based on factors such as the
relevant biological indicator, in their original, individual con- nature of the product and the required limit of microorgan-
tainers. Place the specimens of a group in suitable specimen isms. The method chosen must allow testing of a sufficient
holders that permit each specimen to be exposed to the sample size to judge compliance with the specification. The
sterilizing conditions at a specific location in the BIER cham- suitability of the chosen method must be established.
ber.
Expose the specimens for the required survival time, enter GROWTH PROMOTION TEST, SUITABILITY
the chamber, and remove the holder(s) containing the 10 OF THE COUNTING METHOD AND NEGATIVE
specimens. Repeat the above procedure immediately, or
preheat if a substantial interval has elapsed, so as to sub
您可能关注的文档
最近下载
- 社会组织会费票据管理制度(范本).pdf VIP
- 代理记账业务内部管理规范制度范本.docx(核实添加无关内容) VIP
- 《公路沥青路面施工技术规范》(F40-2004 )【可编辑】.docx VIP
- 光的人眼非视觉生物效应作用剂量 编制说明.pdf
- 多准:天猫啤酒2022年趋势报告.pdf VIP
- 2025年高考政治复习知识清单必修一《中国特色社会主义》【答题模板】.pdf VIP
- 苏S01-2012给水排水图集(无水印).docx VIP
- 制瓶机供料机.doc VIP
- 加油站防汛应急预案.docx VIP
- 泌尿外科利用PDCA循环降低持续膀胱冲洗患者膀胱痉挛的发生率品管圈.pptx VIP
文档评论(0)