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甘油连续生物歧化过程的多目标优化.pdfVIP

甘油连续生物歧化过程的多目标优化.pdf

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Computer Engineering and Applications 计算机工程与应用 2016 ,52(20 ) 235 甘油连续生物歧化过程的多目标优化 徐恭贤,高群王 XU Gongxian, GAO Qunwang 渤海大学 数理学院,辽宁 锦州 121013 College of Mathematics and Physics, Bohai University, Jinzhou, Liaoning 121013, China XU Gongxian, GAO Qunwang. Multi-objective optimization of continuous bio-dissimilation process of glycerol. Computer Engineering and Applications, 2016, 52(20 ):235-241. Abstract :Multi-objective optimization of continuous bio-dissimilation process of glycerol to 1, 3-propanediol is studied. According to a nonlinear dynamic system of enzyme-catalytic kinetics on the continuous bio-dissimilation process of glycerol to 1, 3-propanediol, four objectives are first proposed to maximize the production rate of 1, 3-propanediol, the conversion rate of glycerol bioconversion to 1, 3-propanediol, the conversion rate of glycerol and minimize the concentration of 3- hydroxypropionaldehyde. Then six new multi-objective nonlinear optimization models are established. These multi-objective problems can simultaneously optimize any two of the four objectives above to perform the continuous bio-dissimilation process of glycerol to 1, 3-propanediol. The Normal Boundary Intersection (NBI )method is used to solve the proposed multi-objective optimization problems. A filter strategy is adopted to eliminate the non-global Pareto points generated by the NBI method. Finally, some discussions on the obtained Pareto optimal solution sets and the Pareto fronts for the six multi-objective optimization problems are presented. This kind of analysis can provide a guide for achieving the optimal operation of continuous bio-dissimilation process of glycerol to 1, 3-propanediol. Key words :bioprocess; optimization; multi-objective; optimal operation; Pareto optimal solution 摘 要:研究了甘油连续生物歧化过程的多目标优化。针对甘油连续生物歧化为1,3- 丙二醇过程的还原途径酶催 化非线性动力系统,首先考虑目的产物1,3- 丙二醇的产率、甘油转化为1,3- 丙二醇的转化率、甘油的转化率以及3- 羟基丙醛浓度等四个目标函

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