生物样本库知信行情况问卷的信度和效度分析.pdfVIP

• 478 • 中华医学科研管理杂志 2015 年 12 月第 28 卷第 6 期 Chin J Med Sci Res Manage ,Dec. 2015 ,Vo l. 28 ,No. 6 ，方法研讨· 生物样本库知信行情况问卷的信度和效度分析 蒋聪徐刚王伟业陶哗璇 E摘要】 目的 通过生物样本库知信行情况问卷的信度和效度分析评价其在公众中应用的可行 性。方法 共有 292 名受访者接受问卷调查，并对问卷进行信度、效度评价。结果 主要测量指标的 内在信度 Cronbachsα 系数为 0.850 ，研究参与认知和参与态度 2 个维度的内在信度最高。各维度 得分与总分间的 Spearman 相关系数均大于 o. 5(p0. 01) 。因子分析显示问卷的结构效度较好，3 个 公因子涵盖了研究参与态度、认知和行为，能解释问卷全部内容的 59.2% 。结论 本问卷具有良好 的信度和效度，可用于公众生物样本库知信行情况的相关研究。 E关键词】 生物样本库; 调查问卷; 信度; 效度 Reliability and validity of a questionnaire on cognition , attitude and behavior towards biobanks ] iang Cong , Xu Gang , Wang Weiye , Tao Yexuan. Department of pediatrics , XinHua Hospital Affiliated to Shanghai ] iaotong University School of Medicine , Shanghai 200092 ,P. R. China Corresponding author: Tao Yexuan , Email:taoyx@163.com [Abstract Objective To test and validate the comprehensiveness , usability and reliability of the questionnaire we made for publicity efforts of biobanking activities in China. We aim to learn pub- lic attitudes toward biobanking donation of biological materials , collection and long-term storage for biomedical research. Meth叫s In the cross-sectional study , 292 participants were interviewed with the self-administered questionnaire. The survey questionnaire presents an extensive battery of ques tions on demographic information , participation of previous studies , cognition of biobank and related concepts , opinions on biobank-related issues and trust on healthcare system. Different statistic meth- ods were taken to do item analysis , reliability and validity evaluation. Results The Cronbachsαco efficient of the whole questionnaire was o. 850 and the cognition and attitude were the two factors with the highest internal reliability. All the Spearman correlation coefficients were