武汉市大肠癌危险因素的1_2配比病例对照研究_聂绍发.pdf

1 82 CHINA PUBLICHEAL H 　Vol.18 No.12 Dec 2002 　2002 18 12 :1001-0580(2002)12-1482-03 【】 1 ∶2 (430030)　聂绍发　姚　璇　朱桂宝　张金荣　许奕华　汪　鑫 　:　。　1∶2 , 100 200 Logistic 。　10 、10 、、、、、 , OR 1.114, 1.091, 1.117, 1.490, 2.483, 5.751, 11.531;, OR 0.789;、, OR 0.230, 0.44 1。　、 、。 :;;1 ∶1 ;Logistic + :R181.3 2　　:A 1∶2 Matched Case-control Study on Risk Factors of Colorectal Cancer in Wuhan　NIE Shao-f a, YA OX uan, ZH U Gui- bao, et al.Dep artment of Ep idemiology, ongj i Medical College of Huaz hong University of Science and echnology (Wuhan 430030, China) Abstract:Objective　To investigate the risk factors of colorectal cancer.Methods　A 1∶2 controls data were analysed w ith conditional logistic regression.Results　That the diet fre uency of meat, the fre uency of using oil of animal ten years ago and salted meat, the poor ability of adjusting the mood, the history of gastric and duodenum ulcer and chronic appendicitis, and col- lateral relatives w ho suffered from cancer w ere independent risk factors of colorectal cancer.The corresponding OR w as 1.114, 1.091, 1.117, 1.490, 2.483, 5.751 and 11.531, respectively.Favor of eating soft food w as an independently protec- tive factor, and the corresponding OR w as 0.789.The history of falling ill in respiratory system and coronary heart disease were negatively related risk of colorectal cancer, and the corresponding OR was 0.230 and 0.44 1, respectively.Conclusion　 Colorectal cancer seemed to be related to the dietary factors, the poor ability of adjusting the mood, the history of gastric and duodenum ulcer and chronic appendicitis, and family history of malignant tumors. Key words:colorectal cancer;risk factor;case-control study;conditional logistic regression 〔1〕 　　 2% 。 , 、、 , 1998 ～2000