制备TiO2xNx薄膜陶瓷托槽的抗菌性能.docVIP

制备TiO2-xNx薄膜陶瓷托槽的抗菌性能 王建卫，王 宇，车远倩，朱博武，曹宝成(兰州大学口腔医学院，甘肃省兰州市 730000) 引用本文：王建卫，王宇，车远倩，朱博武，曹宝成. 制备TiO2-xNx薄膜陶瓷托槽的抗菌性能[J].中国组织工程研究，2016，20(34):5039-5044. DOI: 10.3969/j.issn.2095-4344.2016.34.004 ORCID: 0000-0003-0839-4027(曹宝成) 文章快速阅读： 文题释义： 陶瓷托槽：与天然牙相近，然而，由于托槽结构复杂，使得托槽周围容易聚集菌斑且不易清洁，同时，固定矫治装置使得口腔的微生态环境发生变化，使变形链球菌等致龋菌数量增加，引起釉质脱矿等一系列并发症，调查显示，正畸人群中牙釉质脱矿发病率在73%-95%。为了解决这一正畸治疗的并发症，曾有学者尝试在牙面上涂布抗菌药物，在粘接剂中添加抗菌颗粒或在金属托槽上镀抗菌材料，以达到抗菌防龋目的。 纳米TiO2：TiO2-xNx thin films on ceramic bracket surfaces: preparation and antibiotic performance Wang Jian-wei, Wang Yu, Che Yuan-qian, Zhu Bo-wu, Cao Bao-cheng (School of Stomatology, Lanzhou University, Lanzhou 730000, Gansu Province, China) Abstract BACKGROUND: Enamel demineralization has been plaguing doctors and patients in the fixed orthodontic treatment, so we attempt to seek an effective method of reducing its incidence. OBJECTIVE: To prepare TiO2-xNx thin films at different thicknesses on the ceramic bracket surface by sol-gel method followed by detection of antibiotic performance. METHODS: TiO2-xNx thin films at different thicknesses were prepared on the ceramic bracket surface by sol-gel method. The crystal structure, surface morphology and attachment force of these thin films were analyzed by X-ray diffraction, scanning electron microscope and multi-function material surface tester, respectively. The color changes of ceramic brackets before and after coating were evaluated through German VITA Easyshade Advance 4.0 photoelectric color comparator. Antibiotic performance of the ceramic bracket coated with TiO2-xNx thin film for Candida albicans and Streptococcus mutans was evaluated by the flat colony counting method. RESULTS AND CONCLUSION: The prepared TiO2-xNx thin film was anatase type, which had uniform and compact structure, and its X-ray diffraction peaks were elevated with the increase of film thickness. The attachment force of the thickest film was 18.37 N, indicating the thin film has a good adhesion to the ceramic brack