丙泊酚及靶控输注系统概要1.pptVIP

TCI and Propofol(丙泊酚及靶控输注系统) Conflict of Interest(利益冲突) I’ve consulted for propofol(我为丙泊酚做过顾问) AstraZeneca I’ve consulted for remifentanil(我为瑞芬太尼做顾问) Glaxo, Abbott I’ve consulted for companies interested in TCI(我为对靶控输注系统感兴趣的公司顾问) Alaris, B Braun, Medex Pharmacokinetic Concepts(药代动力学概念) Volume of Distribution(分布容积) Clearance(清除率) Half-Life(半衰期) The time required for drug concentrations to decrease by 50%.(药物浓度降低50％所需的时间) 三室模型 Opioid Half-Lives (minutes)(鴉片類製劑的半衰期 --分钟) Opioid Pharmacokinetics(鴉片類製劑药代动力学) Context-Sensitive Half-Time(时效相关半衰期) Propofol Pharmacokinetics(丙泊酚 药代动力学)