1、基因组进化中的遗传学问题.PPT

突变的基本类型 Single nucleotide polymorphism (SNP) Insertion/deletion (s) (Indel) Structural variation, Copy number variation Q:丰富的遗传变异从何而来？ (变异的来源并非十分清楚) Result and discussion 结果3：Indel大小影响SNP累积 结果： 1. 与Indel越近，SNP越高;2. Indel越密集，SNP越高;3. Indel越大，SNP越高. What did we observe? The distance to indel, indel density indel size affect nucleotide divergence (D) Indel was the center of the distribution of mutation-rate Each indel independently affected the surrounding areas. Cause of the mutation-rate change? potential factors Selection Regional-difference of DNA 突变热点区域内SNP与Indel各自发生，即Indel并不影响其