不同人群HCV与其它肝病标志物阳性率的调查.pdfVIP

公共卫生与预防医学2007年第l8卷第6期 J of Pub Health and Prey Med 2007．Vok18。No．6 · 论著 · 不同人群HCV与其它肝病标志物阳性率的调查 陆建华 陈建国 朱健 张永辉 朱源荣 【摘要】目的 了解江苏省启东地区不同人群的HCV等肝病标志物情况。方法 采集肝癌病例、HBsAg阳性 者及自然人群血清标本，用酶免法检测抗一HCV；同时检测ALT、抗一，rITv IgG，HBVM标志物作参考比较。结果 肝 癌病人、HBsAg阳性者和自然人群的抗一HCV阳性率分别为5．11％、1．82％和2．42％，无显著性差异(P0．05)。 未见HCV感染与HBV感染间的联系，与年龄、性别、血型的关系也不大。9例抗一HCV阳性的肝癌患者中有6例伴 有HBsAg阳性，有1例所有的HBVM均为阴性，且ALT和AFP均为阴性。有1例伴有抗一，rITv IgG阳性。结论 启 东地区抗·HCV感染率不高，不同人群间的差别不大；与历史资料比，似有下降的趋势。 【关键词】丙型肝炎病毒(HCV)；HBV；阳性率 【中图分类号】R512．6 【文献标识码】A 【文章编号】1006-2483(2007)06-0034-03 Analysis on the prevalence of anti-HCV infection in different populations in Qidong Area LU Jian—hua， CHEN朐 n—guo，ZHU Jian，ZHANG Yong—hui，ZHU Yuan—rong． Qidong Liver Cancer Institute，Jiangsu 226200，China 【Abstract】 Objective To study the pmvMence of hepatitis C virus(HCV)in different subjects in Qidong area． Methods The seia from the patients witIl liver cancer(LC)，the HBsAg carriers(CR)and general population(GP)were coUected to detect anti-HCV by using ELISA assay．HBV，anti TrVlgG，ALT，and other related markem were also tested for comparison．Results The pmvalence rates of anti-HCV for the three groups were 5．11％ in LC，1．82％ in CR，and 2．42％ in GP，respectively(P0．05)．No relationship WaS found between infections ofHCV，HBV，and 1-IV，and age， sex，and blood types．Six out of 9 liver cancer patients with positive anti—HCV were accompanied with HBsAg．One case，witIl no detectable HBVM，ALT，and AFP；and another one，CO·infected with 兀V．Conclusion The prevalence rate of anti—HCV is not hish in Qidong area．There is no significant difference between patients with liver cancer，carners of HBsAg，and gen· eral population．It 8eenl8 that the pmvalence of anti—HCV，as compared tIl the past data，has show