IHD与CRRT-讲稿.pptVIP

* ???? ????? ??? ???? convective transport?? 50mL/min? ??? ??.(?? high-flux HD?? ???) Diffusive therapy : diffusion? ???? ?? ??? ??? ????? ??????. Diffusion? ?? driving force? blood? dialysate? ?????. ?, ???? ????, ???? ??? diffusion? ? ??? ????. diffusion? ????? membrane thickness??. concentration gradient? contercurrent flow? high-flow rate?? ????. Convective therapy : ????? blood??? solute? ??? ? ???? Mechanism??. convection??? solute? ????? ?? ???? fluid flow? ?? ????. ???? convective membrane? ???? ?? ???? ?? ??? albumin??? ??? ????? membrane??. HF : ????? ??? ?? ???? ????? ???? diffusion? ?? ?? ??? ???. HD : ??? HD?? convective transport? ??? ???. (why:UF? ??, tight membrane) high-flux HD : back-filtration???? ??. tight membrane : not allow for the sieving of large solutes. Combining diffusion and convection : uremic toxin? ??? ?? ????? ???? Small solute? large solute??? ?????? diffusion? convection? ?? HDF??, ????? ?? ?? ?? ???? ??? ? ? ??. HDF? ?????? HD?? 10-15%? ?? urea ???? ?????. * ???? ????? ??? ???? convective transport?? 50mL/min? ??? ??.(?? high-flux HD?? ???) Diffusive therapy : diffusion? ???? ?? ??? ??? ????? ??????. Diffusion? ?? driving force? blood? dialysate? ?????. ?, ???? ????, ???? ??? diffusion? ? ??? ????. diffusion? ????? membrane thickness??. concentration gradient? contercurrent flow? high-flow rate?? ????. Convective therapy : ????? blood??? solute? ??? ? ???? Mechanism??. convection??? solute? ????? ?? ???? fluid flow? ?? ????. ???? convective membrane? ???? ?? ???? ?? ??? albumin??? ??? ????? membrane??. HF : ????? ??? ?? ???? ????? ???? diffusion? ?? ?? ??? ???. HD : ??? HD?? convective transport? ??? ???. (why:UF? ??, tight membrane) high-flux HD : back-filtration???? ??. tight membrane : not allow for the sieving of large solutes. Combining diffusion and convection : uremic toxin? ??? ?? ????? ???? Small solute? large solute??? ?????? diffusion? convection? ?? HDF??, ????? ?? ?? ?? ????