Ig类别的转换和记忆性B细胞的产生 - 返回.PPT

Ig类别的转换和记忆性B细胞的产生 - 返回.PPT

Ig类别的转换和记忆性B细胞的产生 - 返回

Response To T Cell-Dependent Antigen Response To T Cell-Independent Antigen General Rules Of Antibody Production The production of antibodies and their functions Mucosa-Associated Lymphoid Tissue 2. 特异性B细胞的活化与增殖 第一活化信号经由 Igα/β传导入胞内 Deprived from the recognition of BCR to antigen and transduced by Igα-Igβ Igα和Igβ把第一信号传递到胞内,协同受体辅助第一信号的传递。 Signaling By Coreceptors Includes CD21,CD19 and CD81 CD21 and CD19 work together to enhance signaling by the BCR-Igα\Igβ complex. CD32 provide a negative signal in activated B cells Formation Of Germinal Centers 细胞分化和成熟的机制 细胞对TD-Ag的应答特点 特点:1.需要Th的辅助

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