06、执师考点-免疫（06. Master test point - immunization）.doc

06、执师考点-免疫（06. Master test point - immunization） 1, immunity is a series of physiological or pathological reactions that the organism identifies with the antigens of the ego and the non self. 2, the immune system: 1) immune organs: central immune organs, the thymus, bone marrow, peripheral immune organs, spleen and lymph nodes; 2) immune cells: phagocytic cells, dendritic cells, NK cells, T cells and B cells; 3) immune molecules: TCR, BCR, CD, immune molecule globulin and complement. 3. Immune response: the process by which the immune system identifies and clears antigens. 4, innate immunity: also known as innate immunity, is a biological evolution in the long process of gradual formation, is the body against pathogens invasion of the first line of defense. Mainly involved in the early anti infection, anti-tumor, and bear the antigen presentation function. The cells involved in innate immunity include macrophages, dendritic cells, NK cells. Antigen presenting cell is not required. (innate immune response not memory). 5 、 adaptive immunity: also known as acquired immunity, T cells recognize antigen presenting cells by TCR antigen presenting T cell epitope, B cells recognize the B cell epitope by BCR, and produce effector cells. He has three characteristics: specificity, tolerance, and memory. 6, the immune system three functions: immunity, defense, stability, surveillance. 7 antigen: refers to the T cells and B cells, TCR or BCR combination, to promote its value-added, differentiation, production of antibodies or sensitized lymphocytes and combined with them, and then play the immune effects of the material. 8. Two characteristics of antigen: immunogenicity and antigenicity. 9 and hapten: only immunoreactivity, no immunogenicity. 10 、 complete antigen: it has immunoreactivity and immunogenicity. 11. Epitope: a specific chemical group that determines antigenic specificity in antigen molecules. It is the basic structure of specific binding with TCR, BCR or antibody. 12