胆囊结石及胆囊息肉患者术后远期生存质量探究.docVIP

胆囊结石及胆囊息肉患者术后远期生存质量探究【摘要】目的了解不同术式对胆囊结石及胆囊息肉患者生存质量的影响。方法采用消化病生存质量指数(Gastrointestinal Quality of Life Index,GLQI)测定289例采用不同术式治疗的胆囊结石及胆囊息肉患者术后1年以上的生存质量值。结果289例患者的GLQI指数平均分为114.0分,明显低于正常人群124.5分,(P0.05)。保胆术后患者GLQI指数为117.8分,胆囊切除性手术患者术后GLQI指数为109.6分,两者之间差异具有显著性(P0.05)。结论保胆手术术后患者生存质量明显高于胆囊切除性手术患者,切除胆囊能使患者的生存质量明显下降。? 【关键词】 生存质量;胆囊结石;胆囊息肉;保胆手术 ?? Research on the Long?term Quality of Life of Patients With Cholelithiasis and Gallbladder Polyps After Operation RONG wan?shui,LIU Jing?shan,LEI Fu?ming,et al.Department of General Surgery,Shougang Hospital,Beijing University,Beijing,100144,China ? 【Abstract】ObjectiveTo evaluate the influence of different operative way on the quality of life of post?operative patients who suffered from cholelithiasis and gallbladder polyps.MethodsValues in the quality of life of 289 post?operative patients who suffered from cholelithiasis and gallbladder polyps were tested by using gastrointestinal quality of life index.ResultsThe mean GLQI score of 289 patients is 114.0,and much less than that of normal cases whose GLQI score is 124.5(P0.05).ConclusionThe quality of life of patients with cholelithiasis who underwent gallbladder?preserving operation is better than that of patients who underwent cholecystectomy.To excise gallbladder decreases the quality of life of patients.? 【Key words】 Quality of life;Cholelithiasis;Gallbladder polyps;Gallbladder?preserving operation 随着两届全国内镜保胆学术大会的召开,内镜保胆手术已逐渐得到学界的认可;尤其是近两年,内镜保胆技术取得了长足的进步。GLQI生存质量评价体系能全面、客观反映患者的健康状况,评价不同治疗方法对患者健康的影响。应用消化病生存质量指数量表对289例胆石症及胆囊息肉术后患者进行了调查,比较了不同术式对患者生存质量影响的差异,现报告如下。? 1资料与方法? 1.1一般资料选择1998~2008年在我院治疗的胆囊结石、胆囊息肉患者,随机抽取289例为研究对象,采用问卷形式对其进行GLQI评分调查。其中微创保胆取石术(Endoscopic Minimally Invasive Cholecystolithotomy,EMIC)154例,腹腔镜胆囊切除术(laparoscopic cholecystectomy,LC)28例,开腹胆囊切除术(Open cholecystectomy,OC)107例;男性患者109例,女性180例,年龄23~84岁,中位年龄54岁;合并糖尿病32例。随访1~10年,平均2.6年。289例患者的术后并发症情况见表1。? 表1 289例患者的术后并发症发生情况(例) ? 术后并发症开腹胆囊?切除术腹腔镜胆?囊切除术保胆手术 胆囊切除术后综合征102