清中安胃饮治疗湿热中阻型胃溃疡的临床探究.pdfVIP

提 要 (gastric ulcer， ) 目的：观察清中安胃饮治疗湿热中阻型胃溃疡 GU 的临床疗效，并 从理论和临床研究两个方面探讨清中安胃饮治疗湿热中阻型 GU 的机制。方法：临床 选择符合纳入标准的 GU 患者 60 例，随机分为两组，治疗组（30 例）给予清中安胃 饮，对照组（30 例）给予雷贝拉唑，HP 感染患者联合给予阿莫西林、克拉霉素口服 一周，两组均以 6 周为 1 疗程，疗程结束后观察两组的临床疗效，并对治愈患者随访 6 个月以观察远期疗效。结果：临床研究显示，治疗组中医证候疗效、胃镜疗效及溃 疡远期疗效等均优于对照组（P ＜0.01 或 P ＜0.05 ）。治疗组能明显消除或改善 GU 患者胃脘疼痛、脘腹胀满、泛酸烧心、口干口苦、食少纳差等症状，其疗效优于对照 组（P ＜0.05 或 P ＜0.01 ）。两组治疗期间均未发生不良反应。结论：清中安胃饮是 治疗湿热中阻型胃溃疡的有效方剂，其机理可能与清除 HP 、抑酸、抗炎、改善微循 环、增强粘膜屏障功能、促进胃肠运动等有关。 关键词 清中安胃饮；胃溃疡；湿热中阻；临床研究 Clinical Study of “Qing Zhong An Wei Yin” On Gastric Ulcer of Damp-Heat in the Middle Energizer Specialty：Gastroenterology.Internal Medicine of TCM. Author ：Sun minghui Tutor：Professor Lu Guangchao Abstract Objective: To observe the clinical effect and mechanism of “Qing Zhong An Wei Yin” on Gastric Ulcer(GU) of Damp-Heat in the Middle Energizer. Methods: 60 patients with GU were divided into two groups at random:the treatment group and the control group. The treatment group (30 cases) was treated with “Qing Zhong An Wei Yin” ，and the control group (30 cases) was treated with Rabeprazole ,HP infection were treated with Rabeprazole 、Amoxicillin 、Clarithromycin for a week ，and then give Rabeprazole for tin lest time. 6 weeks was set as a course of treatment. The clinical effects were observed during the course and the follow-up survey of 6 months. Results: The effective of TCM syndrome and the improvement of gastroscope are both superior to that of the control group (P ﹤0.01 or P ﹤0.05). Conclusions: “Qing Zhong An Wei Yin”is a effective recipe for Gastric Ulcer(GU) of Damp-Heat