益坤丸合二甲双胍治疗多囊卵巢综合征的临床探究.pdfVIP

提 要 目的：观察我院自制药品益坤丸协同二甲双胍治疗多囊卵巢合综合征患者的疗 效，初步探讨其作用机理。方法：将 46 名诊断为多囊卵巢综合征的患者随机分为治 疗组（23 ）、对照组（23 ）。对照组给予口服二甲双胍；治疗组在对照组口服二甲双胍 的基础上加用益坤丸口服，90 天为一疗程。观察 2 组治疗前后体重指数、性激素、 空腹血糖、空腹胰岛素、临床症状体征等指标，并作统计学分析。结果：本试验表明， 益坤丸合二甲双胍治疗多囊卵巢综合征可以更好地改善多囊卵巢的各项指标及症状。 两组治疗前后对比可见，雄激素(T)、LH/FSH 、空腹血糖（FBG ）在治疗后有显著降 低，可见显著性差异。结论：益坤丸治疗多囊卵巢综合征异常疗效明显，且没有发现 任何毒副作用，安全有效，该疗法能够调节性轴，降低血糖，减轻患者体重，使患者 恢复排卵和月经，与二甲双胍合用治疗多囊卵巢综合征，效果明显。 关键词 益坤丸；二甲双胍；多囊卵巢综合症；临床研究 The Clinical Studies on Polycystic Ovary Syndrome treated by Yikunwan and Metformin Speciality: :the Internal Medicine of TCM Author: Liu Luping Tutor: Feng Jianhua Abstract Object: To test the clinical curative effect of Yikun Wan treating Polycystic Ovary Syndrome (PCOS)and discuss the mechanism during this process, to make more understanding and find more treating-methods about PCOS . Methods. 46 patients of Polycystic Ovary Syndrome were divided randomly into therapy group (23cases) and control group (23 cases ). The control group was treated by the Metformin; The therapy group was treated by Metformin and YikunWan,90 days would be a course of treatment. The patients’s body mass index [BMI]、sex hormone、fasting blood sugar、fasting insulin before and after the treatment of the two groups were detected, the deta would be treated by statistical analysis to get the conclusion. Results: The examination indicate that the PCOS patients，some targets and symptoms were improved by YikunWan and Metformin 。 T 、LH/FSH 、FBG were decreased remarkably in the treatment group, which were statistically different compared with those of the control group 。Conclusion: It shows that in this clinical study YikunWan had effect in treating PCOS, and it had