influence of high-porosity mesh stent on hemodynamics of intracranial aneu- rysm：a computational study.pdfVIP

848 2013,25(6):848-855 DOI: 10.1016/S1001-6058(13)60432-1 Influence of high-porosity mesh stent on hemodynamics of intracranial aneu- * rysm: A computational study QIU Xiao-ning (邱晓宁) Key Laboratory of Education Ministry of China for Power Machinery and Engineering, Shanghai Jiao Tong University, Shanghai 200240, China, E-mail: xiaoning0018@126.com FEI Zhi-min (费智敏) Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 203204, China ZHANG Jue (张珏) Renji Hospital, Shanghai Jiaotong University, Shanghai 200127, China CAO Zhao-min (曹兆敏) Key Laboratory of Education Ministry of China for Power Machinery and Engineering, Shanghai Jiao Tong University, Shanghai 200240, China (Received September 23, 2012, Revised April 2, 2013) Abstract: This paper studies the influence of a High-Porosity Mesh (HPM) stent on the hemodynamic characteristics in the intracra- nial aneurysm based on the Computational Fluid Dynamics (CFD). An idealized basilar tip aneurysm model and a HPM stent model are built. The pulsating blood flow in a cardiac cycle is computationally simulated for non-stented and stented models, to provide a wealth of information of the spatio-temporally varying blood flow field. The influence of the stent placement on the hemodynamic characteristics is analyzed in terms of distributions of velocity, pressure, Wall Shear Stress (WSS) and Energy Loss (EL), which are believed to play an important role in the development and rupture of the aneurysm. The numerical results clearly show that the velo- city, pressure, WSS and EL of the blood flow in the aneurysm are reduced by 30%-40% when the HPM stent is implanted. These computational results may provide valuable hemodynamic information for clini