芍芪椿皮汤治疗大肠湿热型溃疡性结肠炎的临床疗效视察.pdf

提 要 目的：观察芍芪椿皮汤治疗大肠湿热型溃疡性结肠炎的临床疗效并探讨其作用机 理。 方法：在符合纳入标准的病例中选择60例病人，随机分为治疗组30例、对照组 30 例。治疗组给予芍芪椿皮汤水煎内服加美沙拉秦缓释颗粒剂（艾迪莎）口服，对 照组给予美沙拉秦缓释颗粒剂（艾迪莎）口服。对治疗前后主要症状、体征及肠镜粘 膜像等给以评分，并进行统计学处理，进一步观察两组的疗效。 结果：临床研究显示，治疗组临床综合疗效、中医症候疗效、证候积分疗效及肠 镜下黏膜像疗效均优于对照组 （ P＜0.05或P＜0.01）。治疗组能明显改善腹痛、腹泻、 里急后重等症状，对于治疗粘液脓血便两组无明显差异，但是治疗组的有效率大于对 照组。两组治疗期间均未发生明显不良反应。 结论：芍芪椿皮汤能够消除或改善溃疡性结肠炎的临床症状，促使肠道黏膜病变 恢复，疗效确切，无明显副作用，是治疗大肠湿热型溃疡性结肠炎的有效方剂。芍芪 椿皮汤和艾迪莎合用疗效更好，往往能够取得满意疗效，显示出了中西医结合治疗本 病的优越性和广阔前景。 关键词 溃疡性结肠炎；芍芪椿皮汤；大肠湿热型；临床研究 Peony Astragalus Chunpi Decoction in the treatment of large intestine damp-heat ulcerative colitis clinical curative effect observation Speciality: External Medicine of TCM Author: Li Jing Tutor: Prof.Mei Xiaoling Abstract Objective: to investigate the Peony Astragalus Chunpi Decoction in the treatment of large intestine damp-heat ulcerative colitis clinical effect ,and to explore its mechanism. Method:60 cases of patients were randomly divided into treatment group ( 30 cases) and control group ( 30 cases). The treatment group was given Peony Astragalus Chunpi Decoction and Etiasa; the control group was given Etiasa. Through main symptoms, symptom integral and colonic mucous membranes such as contrast, observe 2 groups.Results:clinical studies have shown, the treatment group clinical efficacy, therapeutic efficacy of TCM syndromes, colonoscopy efficacy(P0.05 or P0.01) was significantly better than the control group. The treatment group can significantly improve patient with diarrhea, abdominal pain and tenesmus and other symptoms. The 2 groups did not have adverse reactions.Conclusion:Peony Astragalus Chunpi soup