aktivált t sejt - immunologyunidebhu.pptVIP

* * Immature myeloid cells (IMCs) are part of the normal process of myelopoiesis, which takes place in the bone marrow and is controlled by a complex network of soluble factors that include cytokines such as granulocyte/macrophage colony-stimulating factor (GM-CSF), stem-cell factor (SCF), interleukin-3 (IL-3), FMS-related tyrosine kinase 3 (FLT-3), macrophage colonystimulating factor (M-CSF) and cell-expressed molecules including Notch (not shown). Haematopoietic stem cells (HSCs) differentiate into common myeloid progenitor (CMP) cells and then into IMCs. Normally, IMCs migrate to different