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Microfluid Nanofluid (2010) 8:303–311 DOI 10.1007/s10404-009-0461-2 RESEARCH PAPER Size-controlled synthesis of gold nanoparticles using a micro-mixing system Sung-Yi Yang Æ Fong-Yu Cheng Æ Chen-Sheng Yeh Æ Gwo-Bin Lee Received: 19 March 2009 / Accepted: 24 May 2009 / Published online: 16 June 2009 Springer-Verlag 2009 Abstract A new microfluidic reaction chip capable of Keywords Gold nanoparticles mixing, transporting and controlling reactions has been Vortex-type micro-mixer Micro-pump MEMS developed for the size-tunable synthe