膝关节骨性关节炎非手术治疗的研究进展.pdfVIP

²3122 ² 中华临床医师杂志( 电子版)2016 年10 月第10 卷第20 期 Chin J Clinicians(Electronic Edition),October 15,2016,Vol.10,No.20 ²综述² 膝关节骨性关节炎非手术治疗的研究进展 1 1,2 2 朱瑞博 颜连启 孙钰 【摘要】 膝关节骨性关节炎（KOA ）是一种最常见的膝关节相关的疾病，是一种影响软骨、 软骨下骨、滑膜关节囊、滑液、韧带、半月板和肌肉等结构的以关节和关节软骨破坏为主的退行性 疾病，是与年龄有关的关节病变，多发于中老年人。主要通过物理疗法、运动疗法、健康教育、药 物治疗、自噬疗法、自体富含血小板血浆注射及手术治疗等改变这种关节及关节软骨退变。本文主 要以KOA 的非手术治疗展开综述。 【关键词】 骨关节炎，膝； 药物治疗 1 1,2 2 Research progress of the treatment of osteoarthritis of the knee Zhu Ruibo , Yan Lianqi , Sun Yu . 1Department of Osteology, Xiangya School of Medicine, Central South University, Changsha 410000, China; 2Department of Orthopedics, Subei Peoples Hospital of Jiangsu Province, Yangzhou 225001, China Corresponding author: Yan Lianqi, Email: yanlianqi@126.com 【Abstract 】 Knee osteoarthritis (KOA) is a most common knee joint related disease that influences cartilage, subchondral bone, synovial membrane of articular capsule, synovial fluid, the meniscus, ligaments and muscles structure, and it is a degenerative disease characterized by joints and articular cartilage damage.KOA is an age related joint disease, mainly happens in the elderly. Many treatments, such as physical therapy, exercise therapy, health education, psychological hint treatment, drug therapy, autophagy therapy, autologous platelet rich plasma injection and surgery treatment can change the degeneration of joint and articular cartilage. 【Key words 】 Osteoarthritis, knee; Pharmaceutical 膝关节骨性关节炎（knee osteoarthritis ，KOA ） 疗重点为缓解疼痛，改善关节活动度，增加关节的 是一种最常见的关节相关的疾病，以退行性病理改 强度，减少致残疾病。 [1] 变为基础的骨骼肌肉系统疾患 。这种疾病多见于