基于数据挖掘的周平安教授外感发热用药规律研究 - 环球中医药杂志.pdf

1摇038 环球中医药2016年9月第9卷第9期摇 Global Traditional Chinese Medicine,September2016,Vol郾9,No郾9 ·论著 · 基于数据挖掘的周平安教授外感发热用药 规律研究 李国栋摇 吴志松摇 曹芳摇 王玮摇 焦扬 揖摘要铱摇 目的摇 探索周平安教授治疗外感发热的中药配伍及组方用药规律。 方法摇 筛选整理 周平安教授治疗外感发热医案,对所用药物通过SPSS21.0 和SPSSModeler 18.0进行药物及其性味 归经频数分析、关联规则分析及聚类分析。 结果摇 (1)药物及其性味归经频数分析总结出解表药、 清热药、宣肺止咳药位居前三位;苦寒与辛温之品并用,但以苦寒清热为主;以归属肺经药物为主, 直达病所,兼顾脾胃,或清泄大肠,表里同治。 (2)关联规则分析提取出柴胡、黄芩,炙麻黄、杏仁两 组常用药对及解表药 柴胡+黄芩、解表药 炙麻黄+杏仁两组常见的配伍组合。 (3)聚类分析得出 寅 寅 柴胡、黄芩,炙麻黄、杏仁、生石膏、生甘草,羌活、紫苏叶、荆芥、薄荷,金银花、连翘,射干、桔梗,豆 豉、青蒿、生黄芪等9组药。 结论摇 周平安教授在治疗外感发热时几个用药特点:(1)苦寒辛温并 用,以苦寒清热为主;(2)解表清里,清透兼施;(3)脏腑同治,照顾兼证。 揖关键词铱摇 周平安;摇 外感发热;摇 数据挖掘;摇 用药规律 揖中图分类号铱摇 R254摇 揖文献标识码铱摇 A摇 doi:10郾3969/ j郾issn郾1674鄄1749郾2016郾09郾002 Study on the prescription patterns of professor ZHOU Ping鄄an in the treatment of externally contracted fever based on data mining摇 LI Guo鄄dong, WU Zhi鄄song,CAO Fang,et al.摇 Dongfang Hospital of Beijing University of Chinese Medicine,Beijing 100078,China Corresponding author:JIAO Yang,E鄄mail:yangjiao2013@ 揖Abstract铱摇 Objective摇 To explore the patterns of the composition and prescription of traditional Chinese medicine (TCM) of professor ZHOU Ping鄄an in the treatment of externally contracted fever. Methods摇 The medical records of professor ZHOU Ping鄄an used for treating externally contracted fever were filtered and reorganized,frequency analysis,association rule analysis and cluster analysis were used to analyseflavor and channel tropism of the herbs prescribed,the analysis software were SPSS 21.0 and SPSS Modeler 18.0. Results摇 (1) Frequency analysis showed that exterior鄄resolving,heat鄄clearing and lung鄄facilitating and cough鄄relieving herbswereatthetopthreeof most commonly usedtypesofTCM;cold and bitter with warm and acrid typesof TCMwere combined,while cold andbitter type dominatedto clear heat;herbs affiliated t