细胞病理学（Cellular pathology）.docVIP

细胞病理学（Cellular pathology） Cellular pathology A brief introduction to the book of cellular pathology Cell pathology is a branch of Pathology, and it is also an important part of pathology. Its a science that diagnoses diseases by looking at changes in cells. Looking back at home and abroad, it is found that, more than 100 years ago, in 1838, Miiller first described the morphological changes of cells taken from tumor tissue under light microscopy. In 1847, Pouehet introduced a vaginal cell smear method to observe cytological changes in the menstrual cycle. In 1860, Beale reported for the first time that cancer cells were found in the sputum of patients with throat cancer. In 1864, Sanders found cancer cells in urine from patients with bladder cancer. In 1904, Dufour found malignant cells in the cerebrospinal fluid. In 1909, Marissi successfully detected cancer cells from gastric and esophageal cancers with alkaline solution tube irrigation. However, because of the poor cytology and the high rate of diagnostic errors, it has not been paid much attention to and widely used in clinic. 1928 Papanicolaou by vaginal smear method for diagnosis of cervical cancer, created PAP staining, and in 1954, cytology map, which laid the foundation for the cytology, make it become a real subject. In 1930, Martin and Ellis began using tissue biopsies from crude needles (No. 16~18) and used histopathological and cytologic methods to diagnose neoplastic diseases. In 1974, J.Zajicek published a monograph Aspiration Biopsy Cytolo-gy of needle aspiration cytology, made from pure cytology (Exfoliative Cytology) also become a subject of a wider range of applications. In 1961 L.G.Koss diagnostic cytology and pathological basis of written a book published, the cytology and pathology closely together, and gradually become an important branch of - cell pathological pathological study (Cytopathology). With the deepening of the teaching reform of higher education and the educational ideas of expandin