外用中药喷剂洁美保健露治疗痤疮的进展（The development of the treatment of acne in the treatment of acne）.docVIP

外用中药喷剂洁美保健露治疗痤疮的进展（The development of the treatment of acne in the treatment of acne） , 5 June 4, modern medicine health 2 0 1 3 years on February 2 vol. 2, 9, 8 orders and 4 JMo dMe dH e a l t h e b r u a F r y 2 8, 2 0 1 3, V o 1. 2, 9, N o. 4 Patients with renal insufficiency. (2) hydrophilic receptor blockers, atenolol For the representative, its watch is slow, the bioavailability is not high. The drug has a long period of semi-decaying, but In order to achieve a daily dose, it can improve the patients compliance. Because of the drug Lord To be metabolized by kidney, when kidney function is damaged, easy accumulate poisoning, often need to reduce quantity. As a result of Liver function can be small, liver function impaired patients need not adjust the dose, suitable for liver work Bad patients. (3) B receptor blockers of water lipid and hydrolysis, replaced by bisoprolol The bioavailability of the table is relatively high and can be maintained in the pharmacological work of the central nervous system Using, it also reduces the central gods systematic unresponsive response [1, 6, 1. Pharmacokinetic properties The half-life of the drug is relatively stable From the good. Due to the characteristics of the balanced purging of hepatic and renal double channels, the liver or kidney is determined When the single organ function is light or moderate damage is not easy to accumulate, general need not adjust The dosage of the drug, but when one of the organ function completely fails, its plasma clearance is half decaying The duration may be doubled, and the dosage of the drug needs to be adjusted. In summary, B receptor blockers are selective and non-selective Lipid and hydrophilicity, B receptor blockers are in pharmacokinetic and clinical efficacy There was a big difference, and B receptor blockers had large differences in body size and blood drug concentration The degree does not correspond to certain effects, therefore, in the application of B receptor blockers, t Dont