剪切波弹性成像技术检测颈动脉粥样硬化斑块弹性参数的可靠性评价.PDF

doi:10.3969/j.issn.1003-6350.2015.08.0412 ·论 著· 剪切波弹性成像技术检测颈动脉粥样硬化斑块弹性参数的可靠性评价 高振洋，张海钟 ( 中国人民解放军总医院外科临床部口腔外科，北京 100853) 【摘要】 目的 评价剪切波弹性成像技术对颈动脉粥样硬化斑块弹性参数检测的可靠性。方法 应用剪 切波弹性成像技术对3 例颈动脉粥样硬化患者的斑块在体进行弹性检测，获得135个剪切波传播速度的平均 值。结果 帧间变异系数(CV)变化范围为0.04~0.43 ，帧间变异性较小。组内相关系数(CC)变化范围为0.68~ 0.89 ，P值为0.002~0.005。对每例患者进行的三次检测的剪切波传播速度值之间的差异有统计学意义，三次测量 速度值之间有较高的相关性。结论 剪切波弹性成像技术检测颈动脉粥样硬化斑块弹性参数的结果比较可靠， 可重复性较好。 【关键词】 颈动脉粥样硬化；颈动脉斑块；剪切波弹性成像；弹性参数 【中图分类号】 R543.5 【文献标识码】A 【文章编号】 1003—6350（2015 ）08—1153—03 Assessmentofrepeatabilityforshearwaveelastographytechnologytodetectmechanicalpropertiesofhuman carotidplaques. GAOZhen-yang,ZHANGHai-zhong.DepartmentofOralSurgery,DivisionofSurgeryClinic,Chinese PLAGeneralHospital,Beijing,100853,CHINA 【Abstract】 Objective To quantitatively analyze the variance, and repeatability of mechanical properties of human carotid plaques using shear wave elastography (SWE) technology. Methods We detected three patients of ca- rotid atherosclerosis and acquired 135 mean values of shear wave velocity using SWE Technology. Results In- ter-frame coefficient of variation (CV) values ranged from 0.04 to 0.43. Intra-class correlation coefficient (CC) values (r) ranged from 0.68 to 0.89, with P value of 0.002~0.005. Thus, SWE provided reproducible measurements. There were significant variation and correlation between the values of shear wave velocity for three acquisitions for each po- sition for each patient. Conclusion SWE technology can be used to assess the stability of human carotid plaques, and provides accurate and reproducible assessment. 【Keywords】 Carotid atherosclerosis; Carotid plaque; Shear wave elastography; Mechanical properties 颈动脉粥样硬化(Atherosclerosis ，