26例合并HP感染胆汁反流性胃炎患者抗HP治疗临床观察.docVIP

26例合并HP感染胆汁反流性胃炎患者抗HP治疗临床观察【摘要】目的：观察采用抗HP方法治疗不明原因的合并HP感染的胆汁反流性胃炎患者的疗效情况。方法：将53例不明原因胆汁反流性胃炎合并感染HP的患者按随机数字表法的方法随机分为治疗组和对照组。对照组27例予奥美拉唑、海地特、莫沙必利治疗，治疗组26例在对照组治疗基础上加用阿莫西林、克拉霉素，疗程2周，其余药物与对照组相同，疗程为1个月。观察患者症状改善情况及疗程结束后1月复查胃镜了解胆汁反流及胃黏膜炎症情况、HP转阴情况，并随访6个月观察疾病复发情况。结果：不明原因胆汁反流性胃炎合并感染HP的患者经HP根除治疗同未采用根除治疗比较，前者治愈率、HP转阴率明显好于后者，治愈后6个月复发率前者明显低于后者。结论：不明原因的合并HP感染的胆汁反流性胃炎患者，在常规应用抑酸剂、胃黏膜保护剂和胃动力药物的基础上，应考虑HP根除。 【关键词】 胆汁反流性胃炎；HP;治疗;临床观察 【Abstract】Objective: to observe the treatment by resistance to HP unidentified merger of HP infection bile reverse flow the curative effect of sexual gastritis. Methods: 53 patients with unexplained bile reverse flow sex gastritis amalgamative infection by random Numbers of patients HP method of table method were randomly divided into the treatment group and control group. 27 cases in control group paclobutrazol, Haiti ogilvy mather pull Homer, mossa will the treatment, the treatment group based in 26 cases of control group therapy combined with amoxicillin, the clarithromycin, treatment two weeks, the rest of the drugs and the control group the same treatment for 1 month. Observation patient’s symptoms improved conditions and treatment on January review after signicant understand bile reverse flow and gastric mucosal inflammation, HP, shade, and were followed up for 6 months observation disease recurrence. Results: unexplained bile reverse flow sex gastritis amalgamative infection by HP eradicate the patients HP not with radical therapy treatment compared with shade, HP, the former cure rate was significantly better than the latter, rate of 6 months after curing recurrence rate the former obviously lower than the latter. Conclusion: unexplained merger of HP infection bile reverse flow sex gastritis, in conventional application acid agents and suppression gastric mucosa protectant and stomach, on the basis of dynamic drugs should consider HP eradicated. 【Keywords】Bile reflu gasritis；HP；therapy；clinical observation 【中图分类号】R569【文献标识码】B【文章编号】1005-051