性行为及心理疗法配合他达拉非+氟西汀治疗非器质性早泄临床观察(附352例报告).docVIP

性行为及心理疗法配合他达拉非+氟西汀治疗非器质性早泄临床观察(附352例报告)【摘 要】 目的:观察性行为与心理疗法（停-动-停训练及默算性交抽动的次数）配合他达拉非+氟西汀治疗非器质性早泄的临床疗效。方法：352例确诊为非器质性早泄患者中，年龄22~41岁，平均28.30岁；病程6个月~8年,平均2.6年。随机分为治疗组102例（性交前2~4h口服他达拉非20mg+氟西汀20mg配合性行为与心理疗法）和对照1组79例（性交前2~4h口服氟西汀20mg配合性行为与心理疗法）、对照2组48例（单纯性行为与心理疗法）、对照3组81例（性交前2~4h口服他达拉非20mg+氟西汀20mg）、对照4组42例（性交前2~4h口服氟西汀20mg）。所有病例按每2~4d一次性交的频率，连续6周（10~18次的性交、平均14次）。观察五组治疗后射精潜伏期、患者性生活满意度、妻子性生活满意度的变化。结果：连续治疗6周后，治疗组102例治愈79例、好转12例，治愈率77.45%、有效率89.22%；对照1组79例治愈53例、好转9例，治愈率67.09%、有效率78.48%；对照2组48例治愈25例、好转9例，治愈率52.08%、有效率70.83%；对照3组81例治愈16例、好转21例，治愈率19.75%、有效率45.68%；对照4组42例治愈3例、好转15例，治愈率7.14%、有效率42.86%。有配合性行为与心理疗法的治疗组和对照1组、对照2组的治愈率和有效率，与无配合性行为与心理疗法的对照3组、对照4组相比差异均有显著性意义（P值＜0.01）。结论：性行为与心理疗法作为治疗非器质性早泄的主体，以按需给药的方式配合PDE-5抑制剂（他达拉非）和抗抑郁药（氟西汀）治疗非器质性早泄，通过提高阴茎的耐受力和控制射精的能力，延长射精潜伏期，能够明显提高临床治愈率和有效率，增加性生活满意度。 【关键词】 性行为疗法； 心理疗法； 他达拉非； 氟西汀 Sexual behavior therapy and psychotherapy combined with Tadalafil and Prozac in treatment of non-organic premature ejaculation: a report on 352 cases PENG Jingsheng, ZHAN Feiming Department of Andrology, Guangzhou Xiejia Urological Hospital, Guangdong 510290, China 【Abstract】 Objectives: To observe the therapeutic efficacy of sexual behavior therapy and psychotherapy combined with Tadalafil and Prozac in the treatment of non-organic premature ejaculation. Methods: Three hundred fifty-two patients with non-organic premature ejaculation were randomly divided into one treatment and four control groups. Behavior and psychotherapy were applied to the treatment group in combination with Tadalafil and Prozac, while the other control groups were only treated with Tadalafil and Prozac. Results: After 6 weeks? treatment, treatment group showed significant higher curative and efficacy rates than all the control groups (P0.01). Conclusion: Behavioral and psychotherapy, as the major therapy on premature ejaculation, can significantly improve therapeutic efficiency and enhance sexual life satisfaction when they are combined with Tidalafil and Prozac.