纳洛酮联合氨茶碱及山莨菪碱对新生儿窒息复苏后作用.docVIP

纳洛酮联合氨茶碱及山莨菪碱对新生儿窒息复苏后作用[摘要] 目的 探讨盐酸纳洛酮联合氨茶碱及山莨菪碱在新生儿窒息复苏后的临床疗效及临床应用价值，为新生儿窒息复苏后的临床治疗探索一种更为有效的治疗方法。方法 根据Apgar评分标准，从我院2008年1月～2010年8月住院的窒息复苏后新生儿中，选取符合诊断标准的患儿60例，随机等分为对照组和实验组。治疗过程中两组均采用常规治疗方法，实验组在此基础上，给予纳洛酮、山莨菪碱及氨茶碱治疗。观察两组拥抱反射恢复正常的时间、完全脱离氧气治疗的时间及住院时间等。结果 实验组完全恢复拥抱反射的时间明显短于对照组（P＜0.01）；实验组完全脱离氧气治疗的时间明显短于对照组（P＜0.01）；实验组平均住院天数较对照组明显减少（P＜0.01）。结论 盐酸纳洛酮联合氨茶碱及山莨菪碱在新生儿窒息复苏后的治疗中疗效显著，临床应用价值较高。 [关键词] 纳洛酮；氨茶碱；山莨菪碱；新生儿窒息 [中图分类号] R772.12[文献标识码] B[文章编号] 1673-9701（2011）19-53-02 The Clinical Effects of Naloxone Combined with Aminophylline and Anisodamine on Newborns after Resuscitation YANG Zengjin1LI Huabing2WANG Lei3 1.Department of Obstetrical，Maternal and Child Health Hospital of Zhucheng City，Shandong Province，Zhucheng 262200，China；2.Department of Paediatrics，the Peoples Hospital of Zhucheng City，Shandong Province，Zhucheng 262200，China；3.Department of Paediatrics，Maternal and Child Health Hospital of Laiwu City，Shandong Province，Laiwu 271100，China [Abstract] Objective To study the effects and clinical value of naloxone，aminophylline and anisodamine as adjuvant therapy on newborns after resuscitation. Methods Selected 60 cases by control program of newborns after resuscitation in children diagnostic criteria from our hospital from January 2008 to August 2010. 60 cases of newborns with resuscitation were randomly divided into two groups：control group and treatment group. In both groups，children in both groups had no significant difference in the sex，age，clinical manifestations and organ dysfunction. The common methods were taken in both groups. In the group treatment，naloxone、aminophylline and nisodamine was added，under Evaluation standard，the differences of recovery rate and hospital day of infants between two groups were compared by t test or chi-square test. Results The recovery time of embrace reflex of group treatment was much shorter than that of group control（P＜0.01）；The time from oxygen therapy of group treatment was much shorter than that of group control