胎儿心内强回声光点转归及其临床意义.docVIP

胎儿心内强回声光点转归及其临床意义【摘要】 目的 探讨胎儿心内强回声光点的转归及其临床意义。方法 对2009年在我院做系统产前检查的孕妇行回顾性分析。结果 发现胎儿心室腔内强回声光点53例,发病率约1.3%;一般于18-24周时发现,30周左右自然消失;29例做了染色体检查,仅2例为唐氏高危,余均为低危;多单发且位于左心室;均未发现伴有明显心脏结构畸形。结论 胎儿心内强回声病灶可于孕晚期自然消失,与胎儿心脏畸形无明显相关性,与染色体异常相关性有待近一步观察。 【关键词】胎儿; 心脏; 强回声光点; 【中图分类号】R714.5 【文献标识码】 B 【文章编号】1005-0515(2010)007-008-02 The final and the meaning of fetuss ventricle hyperchogenic foci [ Abstract] Objective To explore the final and the meaning of fetus’s ventricle hyperchogenic foci . Methods giving a retrospective analysis for the pregnant women who were made prenatal examination at my hospital in 2009. Results 53 cases were found ventricle hyperchogenic foci in the fetuses, the incidence of fetus?s ventricle hyperchogenic foci is about 1.3%; generally they were found in 18-24th week of the pregnancy , they disappear naturally in 30th week of the pregnancy ; 29 cases has checked chromosome, only 2 cases is high risk at Downs ,the others is low risk ; most of them are single and in left ventricle ; all of them weren’t found abnormity in heart’s structure Conclusion Fetus’s ventricle hyperchogenic foci can disappear naturally in the late of pregnancy , There isn’t any relativity with heart’s structural abnormity , It should be more observed if it is correlative with chromosome abnormity. [ Key words] ventricle hyperchogenic foci ; Fetus ; Chromosome ; Ultrasonography 在18-24周的胎儿畸形筛查中,许多胎儿被发现出心脏内强回声光点,部分学者提出其为染色体异常的一个标记,引起了孕妇的焦虑, 本研究通过对53例产前发现胎儿心内强回声光点孕妇进行临床追踪随访 ,为进一步临床咨询和指导提供依据。 1 资料与方法 1.1 一般资料 病例来自2009年来我院做系统胎儿检查的9494例孕妇,孕妇年龄21岁-42岁,平均30岁。其中80%孕妇孕期在我院定期检查2～6次,平均3.5次,即9494例中约4000例为不重复病例。 1.2 方法采用MEDISON彩色多普勒超声诊断ACCUVIX-XQ及 PHILIP彩色多普勒超声诊断仪IU22,探头频率2-7MHz,经腹扫查,常规顺序扫查胎儿全身各器官系统及附属结构,胎儿心脏采用四腔心、主动脉长轴、三血管、主动脉弓等多切面扫查。 2 结果 2.1 约4000例不重复病例中,发现胎儿心室腔内强回声光点53例,发病率约1.3%;53例孕妇中强回声光点仅存在于左心室47例,仅存在于右心室1例,同时存在于左右两心室5例,左心室两个强回声光点4例,三个强回声光点1例。 2.2 胎儿心内强回声光点最早18周2天发现,最晚 35周4天消失,一般于18-24周时发现,30周左右消失; 2.3 存在心内强回声光点胎儿合并存在第六脑室1例,合并胃泡小伴羊水多2例(1例失访;1例生后死亡,发现肛门闭锁,脚并趾,手屈曲