阿胶颗粒干法制粒工艺研究.pdfVIP

·1714 · 中草药 Chinese Traditional and Herbal Drugs 第 45 卷 第 12 期 2014 年 6 月 阿胶颗粒干法制粒工艺研究 1 2 1* 1 1 田守生 ，孙四海 ，张 淹 ，辛 杰 ，王春艳 1. 山东东阿阿胶股份有限公司 国家胶类中药工程技术研究中心，山东 聊城 252201 2. 聊城市人民医院，山东 聊城 252000 摘 要：目的 研究阿胶颗粒干法制粒的最佳工艺条件。方法 考察轧轮压力、轧轮转速和送粉速度对颗粒得率的影响，采 用 L 4 2 9(3 ) 正交试验优选阿胶颗粒干法制粒工艺条件。结果 最佳制粒工艺条件为轧辊压力为 60～70 kgf/cm 、送粉速度 17～ 19 r/min、轧轮转速为 10～12 r/min。结论 阿胶颗粒干法制粒工艺的研究，为阿胶颗粒产业化应用和干法制粒技术在动物 类中药中的推广应用提供实验依据。 关键词：阿胶颗粒；干法制粒；正交试验；颗粒得率；动物类中药 中图分类号：R283.6 文献标志码：A 文章编号：0253 - 2670(2014)12 - 1714 - 04 DOI: 10.7501/j.issn.0253-2670.2014.12.011 Study on dry granulation technology for Ejiao granules 1 2 1 1 1 TIAN Shou-sheng , SUN Si-hai , ZHANG Yan , XIN Jie , WANG Chun-yan 1. Shandong Dong-E E-Jiao Co., Ltd., National Engineering Technology Research Center of Rubber Medicine, Liaocheng 252201, China 2. Liaocheng District People’s Hospital, Liaocheng 252000, China Abstract: Objective To study the optimal technological conditions of Ejiao granules by dry granulation. Methods The effects of rolling wheel press, speed, and powder feeding rate on grain yield were studied, and the dry granulation technology for Ejiao granules was optimized using L 4 2 9(3 ) orthogonal test. Results The optimal granulating conditions for the roll pressure was 60—70 kgf/cm , powder feeding rate was 17—19 r/min, and rolling speed was 10—12 r/min. Conclusion The study on the dry granulation technology for Ejiao granules provides the experimental basis for industrial application and spread of dry granulation technology in Chinese animal medicines. Key words: Ejiao granules; dry granulation; orthogonal test; grain yield; Chin