不同胎龄早产儿解脲脲原体定植及先天性肺炎关系.docVIP

不同胎龄早产儿解脲脲原体定植及先天性肺炎关系[摘要] 目的 通过统计不同胎龄早产儿呼吸道解脲脲原体（Uu）定植率，分析不同胎龄早产儿呼吸道Uu定植与先天性肺炎的关系。 方法 采用荧光探针PCR法对89例胎龄34～37周早产儿、61例胎龄＜34周早产儿、80例正常新生儿的咽部分泌物或气管内吸出物进行Uu检测。 结果 ①胎龄34～37周、胎龄＜34周早产儿及对照组Uu检测阳性率分别为30.34%、47.54%、11.25%，胎龄34～37周及胎龄＜34周的早产儿Uu检测阳性率均明显高于对照组，差异有统计学意义（χ2=9.16，χ2=20.03，P ＜ 0.05），且两组间差异也有统计学意义（χ2=4.58，P ＜ 0.05）。②胎龄34～37周患先天性肺炎的早产儿Uu检测阳性率为52.00%，胎龄＜34周患先天性肺炎的早产儿Uu检测阳性率为81.48%，两组间差异有统计学意义（χ2=5.13， P ＜ 0.05）。 结论 解脲脲原体感染与早产有密切关系，且胎龄越小，感染可能性越大，有可能是导致早产的重要原因；早产儿发生先天性肺炎时，尤其是胎龄较小的早产儿，应考虑Uu感染的可能，并进行相应检查，及时给予适宜的抗感染治疗。 [关键词] 解脲脲原体；早产儿；先天性肺炎 [中图分类号] R722.6 [文献标识码] A [文章编号] 1673-7210（2012）07（b）-0017-03 The relationship between ureaplasma urealyticum engraftment in different gestational age of premature babies and congenital pneumonia LIN Zhifeng XIAO Zhengxiang Maternal and Child Care Service Centre of Longgang Distict in Shenzhen city, Guangdong Province, Shenzhen 518172, China [Abstract] Objective To analyze the relationship between ureaplasma urealyticum (Uu) engraftment in different gestational age of premature babies and congenital pneumonia, though statistics of Uu engraftment rate in different gestational age of premature babies. Methods Fluorescent probe PCR method was used to detect Uu in nasopharyngeal secretion and Endotracheal aspirate among 89 cases of preterm infants with gestational age 34-37 weeks, 61 cases of preterm infants with gestational age 34 weeks, and 80 cases of normal newborns. Results ① Uu-positive detection rates of preterm infants with gestational age 34-37 weeks, 34 weeks and the control group were 30.34%, 47.54%, 11.25%. Uu-positive detection rates in preterm infants with gestational age 34-37 weeks and 34 weeks were obviously higher than those in the control group, the differences were statistically significant (χ2=9.16, χ2=20.03, P ＜ 0.05), and the difference between the two groups was statistically significant (χ2=4.58, P ＜ 0.05). ② Uu-positive detection rate of gestational age 34-37 weeks preterm infants with congenital pneumo