山茱萸环烯醚萜苷对穹隆海马伞切断大鼠海马区-首都医科大学学报.PDF

2011 2 F eb. 20 11 32 1 Journal of C apitalM ed ical U niversity V o l. 32 N o. 1 [ do:i 10. 3969/j. issn. 2011. 01. 015] 山茱萸环烯醚萜苷对穹隆海马伞切断大鼠海马区神经元存活和 细胞凋亡调控 子的影响 1, 2, 3 1, 2 1, 2 1, 2 1, 2* 丁月霞 张 丽 叶翠飞 王 文 李 林 1. ; 2. ; 3. ) corne l ir ido id g lyco side, C IG ) SD fmi briafo rnix transection, FFT ) , C IG 28 d, CA 1; W estern b lo tting B cl2Bax C , FFT CA 1 ; CIG 2060180 m g kg- 1 ) W estern blotting , FFT Bc l2 , Bax C; C IG B cl2 , Bax C , CIG FFT , ; ; ; ; ; R 338. 2+ 6 Effects of Cornel Iridoid G lycoside on H i ocam al Neuron Survival and A o tosisregulating Factors in Fimbriafornix Transected Rats 1, 2, 3 1, 2 1, 2 1, 2 1, 2* DIN G Y uex ia , ZHANG L i , YE Cuifei , WANG W en , L I L in 1. D epartmen t of Pharm acology, Xuanw u H osp ital, Cap ital M edical Un ivers ity; 2. K ey La ora tory f or N eurodegenerative D iseases, M inistry of Education; 3. D epartmen t of Pharmacy, Yantai Yuhuangd ing H osp ita,l Yan tai, Shangdong Province) ABSTRACT Objective T o investiga te the e ffects o f corne l ir ido id g lycoside CIG ) on hippocampa l neuron surv iva l and its m echan ism after brain in jury in rats. M ethods R at m ode l o fm echan ica l bra in injury w as induced by fmi br iaforn ix transection FFT ) . CIG w as intragastr ica lly adm inistered for 28 days a fter the operation. N issls sta in ing w as u sed to evalua te neuro