多囊肾病研究进展的.pptVIP

常染色体显性遗传性多囊肾研究进展 Evaluation only. Created with Aspose.Slides for .NET 3.5 Client Profile 5.2.0.0. Copyright 2004-2011 Aspose Pty Ltd. 多囊肾病(PKD) 系肾脏的皮质和髓质出现无数囊肿的一种遗传性肾脏疾病 常染色体显性多囊肾病(ADPKD) 常染色体隐性多囊肾病(ARPKD)两种。 Evaluation only. Created with Aspose.Slides for .NET 3.5 Client Profile 5.2.0.0. Copyright 2004-2011 Aspose Pty Ltd. ADPKD主要表现 肾脏的皮质和髓质出现了无数大小不一的囊肿 它们逐步挤压肾组织，造成肾实质损害，出现血尿、蛋白尿、白细胞尿及高血压， 由于毒素积累，最后形成尿毒症而危及生命。 Evaluation only. Created with Aspose.Slides for .NET 3.5 Client Profile 5.2.0.0. Copyright 2004-2011 Aspose Pty Ltd. ADPKD病理生理 PKDl或PKD2基因突变突变影响肾小管上皮细