血必净注射液治疗慢性阻塞性肺疾病急性加重期临床疗效观察及对内毒素水平影响.pdf

、 111I、、＼1( ＼ —一●● ＼f、、J●( 目 录 OO OOOO OO………………………………………………………………1 中文摘要…O 英文摘要…………………………………………………………………………3 正文 一、AECOPD中医证侯横断面调查 前言……···…···……···…······……O月U舌”””””””一”””””“”“”““。 OAOOOOOO………………······…···………5“一“”““”””““”””””“““．b OOOOOO 实验材料与方法(临床资料)………………………O OO………………6 结果·······················································································8 二、血必净治疗AECOPD疗效观察及对内毒素的影响 OOOOO······…···············O“”””””“””””” OOOOO······OOOIOO””“ OOO···0“‘·····OOOOOOOO 前言······O ”一” O···9”‘可 月U舌”“” 实验材料与方法(临床资料)………………………………………………10 结果······…······…·······“··················································一””·13 分析与讨论…………………………………………………………………16 00000000000········································································27 结论0 参考文献…………………………………………………………………………28 致谢··························································································30 附勇匙··························································································32 文献综述…………………………………………………………………………37 作者简历…………………………………………………………………………42 血必净注射液治疗慢性阻塞性肺疾病急性加重期的临床疗效观察 素水平的影响 涂思义 中文摘要 【目的】 通过探讨慢性阻塞性肺病急性加重期(AECOPD)的中医证侯学特征，进一步明确 床疗效，及对内毒素、血气分析、D一二聚体等的影响。 【方法】 首先，在总结既往医家临床经验和相关文献的基础上，初步确定AECOPD的13种基本 证型及其诊断标准。根据诊断标准及专家意见，制定中医证侯观察表，共收集124例 AECOPD患者，通过中医四诊，记录每个患者的临床症状、体征，并予准确辨证，统计并 分析。 规治疗)和治疗组26例(西医常规治疗+血必净注射液)。两组患者均予控制性吸氧、 抗感染、化痰、解痉、平喘等西医常规治疗，必要时予机械通气治疗，治疗组加用血必 进行临床症状、体征评分，并检测血气分析、D-二聚体、白细胞、中性粒细胞