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氨基酸序列集熵值计算工具实现及应用-生命科学
20 3 Vol. 20, No. 3
2008 6 Chinese Bulletin of Life Sciences Jun., 2008
1004-0374(2008)03-0415-06
( 150001)
Entropy
A
TP391; Q517A
Realization and application of an entropy calculation tool
for amino acid sequences
XU Jin, FENG Bao-long, WANG Qing-yan, LIANG Jin, WANG Jing-fei*
(Haerbin Veterinary Research Institute, CAAS, Haerbin 150001, China)
Abstract: Identification of conservative and variable regions of an amino acid sequence of a protein is important
for predicting its structure and functions. Based on the purposes, an entropy computation software named
Entropy, with functions of frequencies calculation of single amino acid residue and generation of conservative
sequence, was designed and realized, and which was applied to analyze the features of amino acid sequence of
hemagglutinin protein of influenza A virus. The software described in this study provides a useful tool for
amino acid sequence analysis.
Key words: entropy; multiply alignment; influenza virus; hemagglutinin; bioinformatics
[5 ]
1
1.1
( e n t r o p y )
(hemagglutinin, HA) (Rudolf Clausius,1822 1888)1850
[1,2]
HA Entropy
[2 ]
HA 1.2
HA
[3,4]
2007-11-30 2008-02-19
(2006-A-01)
* E-mail: jingfei_wang@
416
1 9 4 8
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