老年急性白血病医院感染的临床特点分析.PDFVIP

·42 · Chin J Nosocomiol Vol. 15 No. 1 2005 ·论 　著· 老年急性白血病医院感染的临床特点分析 洪少杰 , 唐小玲 (汕头市中心医院 , 广东 汕头 515031) 摘要 : 目的 　探讨老年急性白血病患者医院感染的临床特点。方法 　对我院 10 年间 62 例老年急性白血病患者 医院感染发生率、感染部位、致病菌和易感因素等进行回顾性分析 ,并与同期非老年组进行比较。结果 　老年组 发生医院感染率为 72. 5 % ,高于同期非老年组的 33. 9 % , P 0. 01 ; 感染部位以口腔和呼吸系统多见 ; 多部位感 染、重症感染高于非老年组 ;致病菌以革兰阴性杆菌为主 ;骨髓抑制、粒细胞缺乏者感染率明显增高。结论 　老年 急性白血病患者医院感染发生率高 ,骨髓抑制、粒细胞缺乏为主要易感因素 ,治疗应及时应用有效抗生素 ,加强综 合支持治疗。 关键词 : 老年 ; 急性白血病 ; 医院感染 ( ) 中图分类号: R733. 71 　　文献标识码 : A 　　文章编号 : 2005 Hospital Infection in Senile Patients with Acute Leukemia : A Clinical Analysis HONG Shaojie , TANG Xiaoling ( ) Shantou Central Hospital , Shantou 515031 , China Abstract : OBJECTIVE To investigate the clinical features of the hospital infection in the senile patients with acute leukemia. METHODS The hospital infection rate , the infective sites , the pathogenic bacteria and the infectious factors of 62 senile acute leukemia patients during the past 10 years were analyzed retrospectively , and compared with groups of nonsenile patients in the corresponding period. RESULTS The incidence of the hospital infection in the senile patients (72. 5 %) was higher than that of nonsenile ones (33. 9 %) , P 0. 01. The most commonly infective sites were oral cavity and respiratory system. The multiple and serious infection in the senile patients was more than that of nonsenile ones. The common pathogenic bacteria were mainly Gramneg