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神经干细胞优势(The advantages of neural stem cells)
神经干细胞优势(The advantages of neural stem cells)
Stem cell therapy has the advantage of unique due to spinal cord injury and regional homologous cell.
Spinal cord injury is a serious hazard to human health disease, injury in patients below the level of injury exists, sensory and motor reflex and urinary dysfunction, the treatment of spinal cord injury research mainly concentrated in the following aspects: the progression of secondary damage control surgery, including reducing pressure, hormone impact therapy, mild hypothermia, calcium channel blocking excitatory amino acid antagonists, and free radical scavenging. To promote axonal regeneration and repair of damaged myelin, strengthen the plasticity of the central nervous system and promote the regional compensation without damage, including the application of transplantation, nerve cell growth factor. The release or various factors of axonal regeneration inhibition and after spinal cord injury, including the application of anti neurite growth inhibitors, application of gene silencing technology indirectly promoting axonal regeneration. Study on the transplantation of carriers mainly concentrated in the embryonic spinal cord tissue, neural stem cells, peripheral nerve, Schwann cells and gene modified cells function. It is reported that, the carrier of transplantation is helpful to the recovery of the nervous system, and has the advantage of stem cell therapy for spinal cord injury and unique regional homologous cells.
After spinal cord injury, blood spinal cord barrier was damaged, ischemic and hypoxia, a variety of inflammatory factors into the injured area, trigger level cell necrosis and apoptosis associated effect. In the remaining nerve cell injury at the same time, can also cause trauma to the spinal cord edge of spinal cord tissue damage, thus preventing secondary injury is an important content of early treatment. From the perspective of pathophysiological mechanisms, the emergence of local micro environment chan
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