chondrosarcoma of the mobile spine and sacrum移动脊柱和骶骨的软骨肉瘤.pdfVIP

Hindawi Publishing Corporation Sarcoma Volume 2011, Article ID 274281, 4 pages doi:10.1155/2011/274281 Review Article Chondrosarcoma of the Mobile Spine and Sacrum Ryan M. Stuckey and Rex A. W. Marco Department of Orthopaedics, University of Texas Medical School at Houston, 6700 West Loop South, Suite 110, Bellaire, TX 77401, USA Correspondence should be addressed to Rex A. W. Marco, rexmarco@ Received 28 September 2010; Accepted 10 December 2010 Academic Editor: Charles Scoggins Copyright © 2011 R. M. Stuckey and R. A. W. Marco. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Chondrosarcoma is a rare malignant tumor of bone. This family of tumors can be primary malignant tumors or a secondary malignant transformation of an underlying benign cartilage tumor. Pain is often the initial presenting complaint when chondrosarcoma involves the spine. In the mobile spine, chondrosarcoma commonly presents within the vertebral body and shows a predilection for the thoracic spine. Due to the resistance of chondrosarcoma to both radiation and chemotherapy, treatment is focused on surgery. With en bloc excision of chondrosarcoma of the mobile spine and sacrum patients can have local recurrence rates as low as 20%. 1. Introduction 3. Location Chondrosarcoma is a rare malignant bone tumor that Chondrosarcoma can occur within all regions of the spine. produces cartilage matrix. Chondrosarcoma can be subclas- Roughly 20% of chondrosarcoma arises in the cervical spine, sified as a primary malig