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a mechanism of prion propagation朊病毒的传播机制.pdf

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a mechanism of prion propagation朊病毒的传播机制

Open access, freely available online Research Digest Synopses of Research Articles Gene Targeting Turns Mice into Endurance training can enhance the and decreased level of specialized type Long-Distance Runners metabolic performance of muscle types, II contractile proteins in the transgenic and now it appears that training can also mice. Interestingly, these same results DOI: 10.1371/journal.pbio.0020322 induce conversion between ﬁ ber types. were seen when naturally occurring Speciﬁ c changes in gene expression (endogenous) PPARδ levels were Have you ever noticed that long- trigger this oxidative ﬁ ber transformation, stimulated in the normal mice (with distance runners and sprinters seem an orally active compound). specially engineered for their This suggests that muscle ﬁ bers sports? One’s built for distance, can be transformed into type the other speed. The ability to I endurance ﬁ bers by simply generate quick bursts of power or activating the endogenou