原创力文档characterization of micrornas from orientobilharzia turkestanicum, a neglected blood fluke of human and animal health significance特性的小分子核糖核酸orientobilharzia turkestanicum,忽视血吸虫人类和动物健康的意义.pdfVIP
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characterization of micrornas from orientobilharzia turkestanicum, a neglected blood fluke of human and animal health significance特性的小分子核糖核酸orientobilharzia turkestanicum,忽视血吸虫人类和动物健康的意义
Characterization of MicroRNAs from Orientobilharzia
turkestanicum, a Neglected Blood Fluke of Human and
Animal Health Significance
1,2. 1 . 1,3 4 2
Chun-Ren Wang , Min-Jun Xu * , Jing-Hua Fu , Alasdair J. Nisbet , Qiao-Cheng Chang , Dong-
1 1 5 1,2,5
Hui Zhou , Si-Yang Huang , Feng-Cai Zou , Xing-Quan Zhu *
1 State Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Veterinary Parasitology of Gansu Province, Lanzhou Veterinary Research Institute, Chinese
Academy of Agricultural Sciences, Lanzhou, Gansu Province, People’s Republic of China, 2 College of Animal Science and Veterinary Medicine, Heilongjiang Bayi
Agricultural University, Daqing, Heilongjiang Province, People’s Republic of China, 3 College of Animal Science, South China Agricultural University, Guangzhou,
Guangdong Province, People’s Republic of China, 4 Parasitology Division, Moredun Research Institute, Pentlands Science Park, Midlothian, Scotland, United Kingdom,
5 College of Animal Science and Technology, Yunnan Agricultural University, Kunming, Yunnan Province, People’s Republic of China
Abstract
The neglected blood flukes Orientobilharzia spp. belonging to the Platyhelminthes, infect animals in a number of countries
of the world, and cause cercarial dermatitis in humans, as well as significant diseases and even death in economically-
important animals. MicroRNAs (miRNAs) are now considered to be a key mechanism of gene regulation. Herein, we
investigated the global miRNA expression profile of adult O. turkestanicum using next-generation sequencing technology
a
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