craniectomy for malignant cerebral infarction prevalence and outcomes in us hospitals颅骨切除术为恶性脑梗塞发病率和结果在我们医院.pdfVIP
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craniectomy for malignant cerebral infarction prevalence and outcomes in us hospitals颅骨切除术为恶性脑梗塞发病率和结果在我们医院
Craniectomy for Malignant Cerebral Infarction:
Prevalence and Outcomes in US Hospitals
1 2 1 2 1
Brian P. Walcott *, Elena V. Kuklina , Brian V. Nahed , Mary G. George , Kristopher T. Kahle , J. Marc
3 4 1
Simard , Wael F. Asaad , Jean-Valery C. E. Coumans
1 Department of Neurosurgery, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, United States of America, 2 Division for Heart Disease
and Stroke Prevention, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia, United States
of America, 3 Department of Neurosurgery, University of Maryland School of Medicine, Baltimore, Maryland, United States of America, 4 Department of Neurosurgery,
Brown University School of Medicine, Providence, Rhode Island, United States of America
Abstract
Object: Randomized trials have demonstrated the efficacy of craniectomy for the treatment of malignant cerebral edema
following ischemic stroke. We sought to determine the prevalence and outcomes related to this by using a national
database.
Methods: Patient discharges with ischemic stroke as the primary diagnosis undergoing craniectomy were queried from the
US Nationwide Inpatient Sample from 1999 to 2008. A subpopulation of patients was identified that underwent
thrombolysis. Two primary end points were examined: in-hospital mortality and discharge to home/routine care. To
facilitate interpretations, adjusted prevalence was calculated from the overall prevalence and two age-specific logistic
regression models. The predictive margin was t
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