原创力文档crystal structure of atvorf273, a new fold for a thermo- and acido-stable protein from the acidianus two-tailed virusatvorf273的晶体结构,一个新的热,acido-stable蛋白质的折叠acidianus双尾病毒.pdfVIP
- 1、原创力文档（book118）网站文档一经付费（服务费），不意味着购买了该文档的版权，仅供个人/单位学习、研究之用，不得用于商业用途，未经授权，严禁复制、发行、汇编、翻译或者网络传播等，侵权必究。。
- 2、本站所有内容均由合作方或网友上传，本站不对文档的完整性、权威性及其观点立场正确性做任何保证或承诺！文档内容仅供研究参考，付费前请自行鉴别。如您付费，意味着您自己接受本站规则且自行承担风险，本站不退款、不进行额外附加服务；查看《如何避免下载的几个坑》。如果您已付费下载过本站文档，您可以点击 这里二次下载。
- 3、如文档侵犯商业秘密、侵犯著作权、侵犯人身权等，请点击“版权申诉”（推荐），也可以打举报电话：400-050-0827(电话支持时间：9:00-18:30)。
- 4、该文档为VIP文档，如果想要下载，成为VIP会员后，下载免费。
- 5、成为VIP后，下载本文档将扣除1次下载权益。下载后，不支持退款、换文档。如有疑问请联系我们。
- 6、成为VIP后，您将拥有八大权益，权益包括：VIP文档下载权益、阅读免打扰、文档格式转换、高级专利检索、专属身份标志、高级客服、多端互通、版权登记。
- 7、VIP文档为合作方或网友上传，每下载1次， 网站将根据用户上传文档的质量评分、类型等，对文档贡献者给予高额补贴、流量扶持。如果你也想贡献VIP文档。上传文档
查看更多
crystal structure of atvorf273, a new fold for a thermo- and acido-stable protein from the acidianus two-tailed virusatvorf273的晶体结构,一个新的热,acido-stable蛋白质的折叠acidianus双尾病毒
Crystal Structure of ATVORF273, a New Fold for a Thermo-
and Acido-Stable Protein from the Acidianus Two-Tailed
Virus
1 ´ 1 1¤ 2
Catarina Felisberto-Rodrigues , Stephanie Blangy , Adeline Goulet , Gisle Vestergaard ,
1 2 ´ 1
Christian Cambillau , Roger A. Garrett , Miguel Ortiz-Lombardıa *
´
1 CNRS, Aix-Marseille Universite, AFMB, UMR 7257, Campus de Luminy, Marseille, France, 2 Archaea Centre, Department of Biology, University of Copenhagen,
Copenhagen, Denmark
Abstract
Acidianus two-tailed virus (ATV) infects crenarchaea of the genus Acidianus living in terrestrial thermal springs at extremely
high temperatures and low pH. ATV is a member of the Bicaudaviridae virus family and undergoes extra-cellular
development of two tails, a process that is unique in the viral world. To understand this intriguing phenomenon, we have
undertaken structural studies of ATV virion proteins and here we present the crystal structure of one of these proteins,
ATVORF273 . ATVORF273 forms tetramers in solution and a molecular envelope is provided for the tetramer, computed from
small-angle X-ray scattering (SAXS) data. The crystal structure has properties typical of hyperthermostable proteins,
including a relatively high number of salt bridges. However, the protein also exhibits flexible loops and surface pockets.
Remarkably, ATVORF273 displays a new a zb protein fold, consistent with the absence of homologues of this pro
您可能关注的文档
- conditional stat1 ablation reveals the importance of interferon signaling for immunity to listeria monocytogenes infection条件stat1消融了干扰素信号的重要性为单核细胞增多性李斯特氏菌感染的免疫力.pdf
- confocal laser scanning microscopy evaluation of an acellular dermis tissue transplant (epiflex？)共焦激光扫描显微镜评估的非细胞真皮组织移植(epiflex ).pdf
- computational protein design validation and possible relevance as a tool for homology searching and fold recognition计算蛋白质设计验证和可能的相关性作为同源性搜索工具和折叠识别.pdf
- congenic mice confirm that collagen x is required for proper hematopoietic development句老鼠证实胶原x是适当的造血所需的发展.pdf
- conserved alternative splicing and expression patterns of arthropod n-cadherin守恒的可变剪接和节肢动物n-cadherin表达模式.pdf
- conserved immune recognition hierarchy of mycobacterial peppe proteins during infection in natural hosts守恒的分枝杆菌的免疫识别层次peppe蛋白质在自然宿主感染.pdf
- conserved regulation of p53 network dosage by microrna–125b occurs through evolving mirna–target gene pairs守恒的p53的监管网络用量通过微rna - 125 b发生演变mirna-target基因配对.pdf
- constructing fluorogenic bacillus spores (f-spores) via hydrophobic decoration of coat proteins构建fluorogenic芽孢杆菌孢子(f-spores)通过蛋白质疏水性装饰的外套.pdf
- conservation and variability of west nile virus proteins西尼罗河病毒蛋白质的保护和可变性.pdf
- construction of transgenic plasmodium berghei as a model for evaluation of blood-stage vaccine candidate of plasmodium falciparum chimeric protein 2.9建设的转基因鼠模型评价blood-stage恶性疟原虫嵌合蛋白2.9的候选疫苗.pdf
- crystal structure of a human single domain antibody dimer formed through vh-vh non-covalent interactions晶体结构的单域抗体通过vh-vh共价相互作用形成二聚体.pdf
- crystal structure of bfr a from mycobacterium tuberculosis incorporation of selenomethionine results in cleavage and demetallation of haem晶体结构的bfr从结核分枝杆菌的硒代蛋氨酸解理和demetallation血红素.pdf
- crystal structure of bamb from pseudomonas aeruginosa and functional evaluation of its conserved structural features晶体结构的bamb铜绿假单胞菌的守恒的结构特点和功能评价.pdf
- crystal structure of cryptosporidium parvum pyruvate kinase隐孢子虫的晶体结构以及丙酮酸激酶.pdf
- crystal structure of der f 7, a dust mite allergen from dermatophagoides farinae晶体结构der f 7日尘螨过敏原从dermatophagoides farinae.pdf
- crystal structure of diedel, a marker of the immune response of drosophila melanogaster晶体结构diedel,黑腹果蝇免疫反应的一个标志.pdf
- crystal structure of enhanced green fluorescent protein to 1.35 ？ resolution reveals alternative conformations for glu222增强型绿色荧光蛋白的晶体结构1.35 分辨率显示替代glu222构象.pdf
- crystal structure of the atpase domain of the human aaa+ protein parapleginspg7atp酶的晶体结构域的人类蛋白质parapleginspg7 aaa +.pdf
- crystal structure of outer membrane protein nmb0315 from neisseria meningitidis外膜蛋白的晶体结构nmb0315脑膜炎奈瑟菌.pdf
- cryptococcal meningitis treatment strategies in resource-limited settings a cost-effectiveness analysis隐球菌脑膜炎治疗策略在资源有限的环境成本效益分析.pdf
文档评论（0）