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- 2017-09-01 发布于上海
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dna nicks promote efficient and safe targeted gene correctiondna缺口促进高效和安全目标基因修正
DNA Nicks Promote Efficient and Safe Targeted Gene
Correction
Luther Davis1,3, Nancy Maizels1,2,3*
1 Department of Immunology, University of Washington School of Medicine, Seattle, Washington, United States of America, 2 Department of Biochemistry, University of
Washington School of Medicine, Seattle, Washington, United States of America, 3 Northwest Genome Engineering Consortium, Seattle, Washington, United States of
America
Abstract
Targeted gene correction employs a site-specific DNA lesion to promote homologous recombination that eliminates
mu
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