dna sequences shaped by selection for stabilitydna序列的选择稳定.pdfVIP

DNA Sequences Shaped by Selection for Stability Martin Ackermann1,2*, Lin Chao1 ¨ 1 Division of Biological Sciences, University of California San Diego, La Jolla, California, United States of America, 2 ETH Zurich, Theoretical Biology, Zurich, Switzerland The sequence of a stretch of nucleotides affects its propensity for errors during replication and expression. Are proteins encoded by stable or unstable nucleotide sequences? If selection for variability is p