endocytosis-independent function of clathrin heavy chain in the control of basal nf-κb activationendocytosis-independent功能的网格蛋白重链的控制基底nf-κb激活.pdfVIP

Endocytosis-Independent Function of Clathrin Heavy Chain in the Control of Basal NF-kB Activation ´ Man Lyang Kim, Isabel Sorg, Cecile Arrieumerlou* Biozentrum, University of Basel, Basel, Switzerland Abstract Background: Nuclear factor-kB (NF-kB) is a transcription factor that regulates the transcription of genes involved in a variety of biological processes, including innate and adaptive immunity, stress responses and cell proliferation. Constitutive or excessive NF-kB activity has been associate