高血压及血脂-同型半胱氨酸关系探究.docVIP

高血压及血脂\同型半胱氨酸关系探究[摘要] 目的：探讨高血压与血脂、同型半胱氨酸的关系。方法：选取高血压患者及血压正常人群各250例，并对高血压患者进行分级；所有患者于早上抽取空腹静脉血测定三酰甘油（TG）、总胆固醇（TC）、高密度脂蛋白胆固醇（HDL-C）、低密度脂蛋白胆固醇（LDL-C）、同型半胱氨酸（Hcy）。结果：高血压组和正常对照组比较，TG、Hcy、TC和LDL-C差异有高度统计学意义（P＜0.01），HDL-C无明显差异。TG、TC、LDL-C、Hcy均随着血压的升高而升高，HDL-C随着血压的升高而逐步降低；男性高血压组比女性高血压比较，TG和Hcy差异有高度统计学意义（P＜0.01），TC、HDL-C和LDL-C无差异。结论：高血压与血脂、Hcy存在密切的相关性，加强心血管健康保健知识和干预措施教育，促使人民自觉地采纳有益健康的行为和生活方式，对于消除或减轻影响健康的危险因素，预防疾病，促进健康和提高生活质量具有重要意义。 [关键词] 高血压；血脂；同型半胱氨酸 [中图分类号] R544.1[文献标识码] C [文章编号]1673-7210（2011）08（a）-087-03 Relations research of high blood pressure, blood fat, homocysteine LUO Qizhi, HUANG Hua, CHEN Qun, LI Yan, LIU Jian 1.Department of Clinical Laboratory, the Second People’s Hospital of Longgang District, Guangdong Province, Shenzhen 518112, China; 2.Department of Physical Examination, the Second People’s Hospital of Longgang District, Guangdong Province, Shenzhen 518112, China [Abstract] Objective: To study relationship of blood pressure and serum lipids, homocysteine. Methods: 250 cases of patients with hypertension and 250 cases with normal blood pressure were selected, and the high blood pressure was classified; to detect triglyceride (TG), total cholesterol (TC), high density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), homocysteine (Hcy) in the morning fasting blood of two groups. Results: TG, Hcy, TC and LDL-C of the hypertension group and control group were significantly different (P＜0.01), HDL-C of two groups had no obvious difference. TG, TC, LDL-C, Hcy increased with the increase of blood pressure, HDL-C decrease with the increase of blood pressure; TG, Hcy had significant difference between men and women patients with hypertension (P 1.3 统计学方法 采用SPSS 13.1软件包进行分析，计量资料以均数±平均值（x±s）表示，组间数据处理经方差齐性检验后，采用两标本t检验。 2 结果 2.1两组血脂、Hcy的水平结果比较 高血压组和正常对照组比较，TG 、Hcy差异有高度统计学意义（P＜0.01），TC和LDL-C差异有统计学意义（P＜0.05），两组HDL-C无明显差异。见表1。 表1 高血压组与正常对照组检测结果比较（x±s） 注：与对照组比较，**P＜0.01，*P＜0.05 2.2 各级的高血压组与正